Low-dose liquorice ingestion resulting in severe hypokalaemic paraparesis, rhabdomyolysis and nephrogenic diabetes insipidus
نویسندگان
چکیده
In daily practice hypokalaemia is frequently observed. It can be accompanied by various adverse events and can even be life threatening. Frequent causes are intestinal and urinary loss, i.e. diarrhoea or use of diuretics. Glycyrrhizin-containing substances, such as liquorice, are a well-known but rare cause of hypokalaemia. They can induce an apparent mineralocorticoid excess-like syndrome, often accompanied by hypertension, metabolic alkalosis, sodium retention and renal potassium wasting [1]. We will discuss a case of liquorice-induced hypokalaemia causing serious electrolyte disorders and severe clinical symptoms.
منابع مشابه
Severe hypokalaemic paralysis and rhabdomyolysis due to ingestion of liquorice.
Chronic ingestion of liquorice induces a syndrome with findings similar to those in primary hyperaldosteronism. We describe a patient who, with a plasma K+ of 1.8 mmol/l, showed a paralysis and severe rhabdomyolysis after the habitual consumption of natural liquorice. Liquorice has become widely available as a flavouring agent in foods and drugs. It is important for physicians to keep liquorice...
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